Gene interactions and pathways from curated databases and text-mining

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JUN — MMP24

Text-mined interactions from Literome

Westermarck et al., FASEB J 1999 (Neoplasm Invasiveness...) : This review will summarize the current view on the role of MMPs in tumor growth, invasion, and survival, and focus on the role of mitogen activated protein kinases and AP-1 and ETS transcription factors in the regulation of MMP gene expression during invasion process
Sato et al., Cancer Res 2002 (Fibrosarcoma...) : These results suggest that nobiletin inhibits tumor cell invasive activity not only by suppressing the expression of MMPs but also augmenting TIMP-1 production in tumor cells, and that the nobiletin mediated inhibition of activator protein-1 binding activity is at least partly involved in the suppression of MMP expression
Kajanne et al., J Cell Physiol 2007 : Here we provide genetic and biochemical evidence that EGF-R- and AP-1 mediated signals are required for MMP expression and collagen contraction in fibroblasts
Hammaker et al., Arthritis Res Ther 2007 (Arthritis, Rheumatoid) : c-Jun N-terminal kinase (JNK) contributes to metalloproteinase ( MMP ) gene expression and joint destruction in inflammatory arthritis
Oliver et al., J Rheumatol 2007 (Arthritis, Experimental...) : We evaluated whether a vanadium AP-1 inhibitor could reduce MMP expression and subsequent joint damage in CIA
Chan et al., International journal of molecular sciences 2011 : In the current study, pretreatment with nitric oxide ( NO ) scavengers inhibited PDT induced mitochondrial membrane potential ( MMP ) changes, activation of caspase-9, caspase-3, p21 activated protein kinase 2 (PAK2) and c-Jun N-terminal kinase (JNK) , and gene expression of p53 and p21 involved in apoptotic signaling
Lee et al., J Dermatol Sci 2013 : In UVB irradiated HaCaT cells, 8-oxo-dG inhibited ROS production, subsequent activation of mitogen activated protein kinase ( MAPK ), ATF-2, and c-Jun , and MMP expression