Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MSK38

Text-mined interactions from Literome

Ryder et al., J Biol Chem 2000 : Stimulation of MSK1 in contracting skeletal muscle required the activation of both ERK and p38 ( MAPK )
Gupta et al., J Biol Chem 2002 (MAP Kinase Signaling System) : ATF1 can be phosphorylated by mitogen- and stress activated protein kinase 1 ( MSK1 ), which is activated by EGF and ERK1/2
Song et al., J Biol Chem 2003 (Inflammation...) : Our results also indicate that the activation of mitogen- and stress activated protein kinase 1 ( MSK1 ) and cAMP-response element binding protein and cAMP-response element signaling cascades via ERK and p38 MAP kinases are crucial aspects of the intracellular mechanisms that mediate MUC5AC gene expression
Vicent et al., Mol Cell 2006 : Five minutes after hormone treatment, Erk activation leads to phosphorylation of the progesterone receptor (PR), activation of Msk1 , and recruitment of a complex of the three proteins to a nucleosome on the MMTV promoter
Sindreu et al., Neuron 2007 (Calcium Signaling) : Ca2+ -stimulated adenylyl cyclases regulate ERK dependent activation of MSK1 during fear conditioning
Putignano et al., Neuron 2007 (MAP Kinase Signaling System) : In juvenile mice, visual stimulation that activates CREB mediated gene transcription also induced ERK dependent MSK and histone H3 phosphorylation and H3-H4 acetylation, an epigenetic mechanism of gene transcription activation
Nagy et al., J Mol Cell Cardiol 2007 (MAP Kinase Signaling System) : Since CREB is a downstream target of MSK-1 ( mitogen- and stress activated protein kinase-1 ) situated at the crossroad of ERK ( extracellular receptor kinase ) and p38MAPK signaling pathways, we reasoned that MSK-1 could be a downstream molecular target for p38MAPK and ERK signaling in the IPC hearts
Clark et al., J Neurochem 2007 : Contrasting roles of neuronal Msk1 and Rsk2 in Bad phosphorylation and feedback regulation of Erk signalling
Besnard et al., J Neurosci 2011 : In response to cocaine, ERK controls the phosphorylation levels of both mitogen and stress activated protein kinase 1 ( MSK-1 ), a nuclear kinase involved in histone H3 ( Ser10 ) and cAMP response element binding protein phosphorylation, and Elk-1, a transcription factor involved in serum response element ( SRE ) -driven gene regulations
Deak et al., EMBO J 1998 : MSK1 is activated in vitro by MAPK2/ERK2 or SAPK2/p38