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CASP4 — NUAK1
Text-mined interactions from Literome
Suzuki et al., Oncogene 2003
(Carcinoma, Hepatocellular...) :
Western blotting analysis revealed that both TRAIL and glucose starvation induced Bid cleavage and FLIP degradation following caspase 8 activation in a time dependent manner, and
ARK5 overexpression clearly
delayed Bid cleavage, FLIP degradation, and
caspase 8 activation
Suzuki et al., Oncogene 2004
:
FLIP was expressed in only ARK5 mRNA expressing cell lines, and
ARK5/AS induced FLIP cleavage in a
caspase-6 dependent manner ... Active ARK5 was found to phosphorylate wild-type caspase-6 in vitro, but not caspase-6/SA, and the prevented activation of
caspase-6 was
promoted due to its phosphorylation by active
ARK5 in vitro