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MAPK8 — OLR1

Text-mined interactions from Literome

Li et al., Circulation 2000 : Activation of mitogen activated protein kinase ( MAPK ) may play a critical role in signal transduction in ox-LDL mediated alteration in MCP-1 expression, since antisense LOX-1 , but not the sense LOX-1, completely inhibited the ox-LDL induced MAPK activation
Iwai-Kanai et al., Circulation 2001 (Heart Failure) : Antioxidant catalase also blocked LOX-1 induced apoptosis as well as activation of p38 MAPK ... These findings demonstrate that LOX-1 expression in cardiac myocytes is induced by neurohormonal factors activated in heart failure and that LOX-1 dependent apoptosis in these cells requires p38 MAPK , a component of oxidant stress-sensitive signaling pathways
Kobayashi et al., Hypertension 2005 (Glomerulosclerosis, Focal Segmental...) : Eplerenone shows renoprotective effect by reducing LOX-1 mediated adhesion molecule, PKCepsilon-MAPK-p90RSK , and Rho-kinase pathway