Gene interactions and pathways from curated databases and text-mining

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MAPK10 — PAK2

Text-mined interactions from Literome

Zang et al., J Biol Chem 2002 : The extent of binding to Raf-1 is correlated with the ability of Pak to phosphorylate Raf and induce mitogen activated protein kinase activation
Rousseau et al., Cell Signal 2006 (MAP Kinase Signaling System) : We also show that the activation of p38alpha MAPK in response to CXCL12 requires the p21 activated protein kinases (PAK)-1 and PAK-2
De la Mota-Peynado et al., J Biol Chem 2011 (MAP Kinase Signaling System) : Collectively, our results identify the Erk3 protein as a novel class I Pak substrate and further suggest a role for Pak kinase activity in atypical MAPK signaling
Huang et al., Mol Cell Biol 1998 : These data indicate that separate signals are required for activation and inactivation of Paks and that, in contrast to other cell types, activated Pak does not trigger activation of JNK or p38-MAPK in neutrophils