Gene interactions and pathways from curated databases and text-mining

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IL6 — PDCD4

Text-mined interactions from Literome

Lee et al., Curr Eye Res 2013 : Down-regulation of PDCD4 by PDCD4 siRNA transfection reduced TNF-a induced IL-6 and IL-8 secretion from orbital fibroblasts
Wilson et al., Nature 1994 : Interleukin-1 beta converting enzyme ( ICE ) processes an inactive precursor to the proinflammatory cytokine, interleukin-1 beta, and may regulate programmed cell death in neuronal cells
Oritani et al., Blood 1999 : Therefore, activation of Stat3 is essential for IL-6 induced macrophage-differentiation and programmed cell death in this model