Vidal et al., Thromb Haemost 2005
:
We previously demonstrated that MNNG induced the transcriptional activity of the plasminogen activator inhibitor-1 ( PAI-1 ) gene in a p53 dependent manner
Kumar et al., Arterioscler Thromb Vasc Biol 2011
:
Conversely, overexpression of p53 suppressed endothelial NO synthase and thrombomodulin expression and stimulated plasminogen activator inhibitor 1 and endothelin-1 expression
Bhandary et al., Am J Physiol Lung Cell Mol Physiol 2012
(Acute Lung Injury...) :
We therefore sought to determine whether p53 mediated inhibition of urokinase-type plasminogen activator ( uPA ) and induction of plasminogen activator inhibitor-1 ( PAI-1 ) contribute to ATII cell apoptosis that precedes the development of PF
Bhandary et al., Am J Pathol 2013
(Lung Injury...) :
We used a mouse model of bleomycin (BLM) induced lung injury to understand the involvement of p53 mediated changes in urokinase-type plasminogen activator ( uPA ) and plasminogen activator inhibitor-1 ( PAI-1 ) levels in the regulation of alveolar epithelial injury
Kunz et al., Nucleic Acids Res 1995
:
Differential regulation of plasminogen activator and inhibitor gene transcription by the tumor suppressor p53