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PORCN — WNT11
Pathways - manually collected, often from reviews:
-
KEGG Wnt signaling pathway:
PORCN
→
WNT1/WNT10A/WNT10B/WNT11/WNT16/WNT2/WNT2B/WNT3/WNT3A/WNT4/WNT5A/WNT5B/WNT6/WNT7A/WNT7B/WNT8A/WNT8B/WNT9A/WNT9B
(protein-protein, activation)
Text-mined interactions from Literome
Wang et al., Nat Genet 2007
(Focal Dermal Hypoplasia) :
Mutations in X-linked
PORCN , a putative
regulator of
Wnt signaling, cause focal dermal hypoplasia
Grzeschik et al., Nat Genet 2007
(Focal Dermal Hypoplasia) :
Deficiency of
PORCN , a
regulator of
Wnt signaling, is associated with focal dermal hypoplasia
Biechele et al., Development 2013
(Wnt Signaling Pathway) :
Porcn dependent
Wnt signaling is not required prior to mouse gastrulation ... Our studies highlight the importance of Wnt3 and Wnt7b for embryonic and placental development but suggest that endogenous
Porcn dependent
Wnt secretion does not play an essential role in either implantation or blastocyst lineage specification