Gene interactions and pathways from curated databases and text-mining

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ILK — PPP1R14B

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: PPP1R14B → ILK (directlyIncreases, ILK Activity, PPP1R14B Activity)
    Evidence: We conclude that ILK may activate smooth-muscle contraction both directly, via phosphorylation of myosin, and indirectly, via phosphorylation and activation of CPI-17 and PHI-1, leading to inhibition of MLCP.
  • OpenBEL Selventa BEL large corpus: PPP1R14B → ILK (directlyIncreases, PPP1R14B Activity)
    Evidence: We conclude that ILK may activate smooth-muscle contraction both directly, via phosphorylation of myosin, and indirectly, via phosphorylation and activation of CPI-17 and PHI-1, leading to inhibition of MLCP.