Gene interactions and pathways from curated databases and text-mining

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ATP5O — PRKAB1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Blair et al., Am J Physiol Endocrinol Metab 2009 : A myosin II ATPase inhibitor reduces force production, glucose transport, and phosphorylation of AMPK and TBC1D1 in electrically stimulated rat skeletal muscle
Hallows et al., Am J Physiol Cell Physiol 2009 : Here we examined whether the metabolic sensor AMP activated protein kinase (AMPK) regulates this PKA induced V-ATPase apical membrane accumulation ... In summary, our findings suggest that AMPK inhibits PKA mediated V-ATPase apical accumulation in epididymal clear cells, that both kinases directly phosphorylate the V-ATPase A subunit in vitro and in vivo, and that AMPK inhibits PKA dependent phosphorylation of this subunit
Benziane et al., Am J Physiol Cell Physiol 2009 : The effect of A-769662 on sodium pump is due to direct inhibition of the Na ( + ) -K ( + ) -ATPase activity, rather than AMPK activation
Gong et al., American journal of physiology. Renal physiology 2010 : Here, we examined the regulation of V-ATPase subcellular localization in intercalated cells by PKA and AMPK in rat kidney tissue slices ex vivo
Ingwersen et al., J Membr Biol 2011 : Na, K-ATPase activity in mouse muscle is regulated by AMPK and PGC-1a
Benziane et al., J Biol Chem 2012 : Whether AMPK activation affects Na ( + ), K ( + ) -ATPase activity in skeletal muscle remains to be determined ... Cyanide induced artificial anoxia, as well as a direct AMPK activator ( A-769662 ) also increase AMPK phosphorylation and Na ( + ), K ( + ) -ATPase activity ... Moreover, AICAR triggered dephosphorylation of the Na ( + ), K ( + ) -ATPase was prevented in L6 myotubes deficient in PP2A-specific protein phosphatase methylesterase-1 ( PME-1 ), indicating a role for the PP2A·PME-1 complex in AMPK mediated regulation of Na ( + ), K ( + ) -ATPase