Gene interactions and pathways from curated databases and text-mining

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IL10 — PTGS1

Text-mined interactions from Literome

Moon et al., Inflamm Res 1999 (Inflammation) : COX-1 and COX-2 protein and mRNA expression was determined by BMMC in the presence of KL, LPS and IL-10
Fernández-Morata et al., Clin Exp Allergy 2000 : Pro-inflammatory cytokines, dexamethasone and IL-10 had no effect on COX-1 mRNA expression
Li et al., Phytomedicine 2009 (Arthritis, Experimental...) : The results showed that comparing with untreated CIA mice, treated with MA dose-dependently suppressed the clinical arthritis score and joints tissues pathological damage, reduced the proliferation of spleen cells, plasma levels of TNF-alpha and IL-6, synovial tissues PGE ( 2 ) production and COX-2 protein expression, however, the expression of COX-1 in synovial tissues did not change and the plasma levels of IL-10 were increased
Mertz et al., J Biol Chem 1994 : In contrast, PGHS-1 , the constitutive PGHS, was not affected by IL-10
Endo et al., J Immunol 1996 : In contrast, cyclooxygenase-1 protein and mRNA were hardly detected in monocytes that were incubated with or without LPS in the presence or absence of IL-4, IL-10 , and IL-13
Longo et al., Mediators Inflamm 1998 : The role of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide and interleukin-1 stimulated enterocyte prostanoid formation