Gene interactions and pathways from curated databases and text-mining

◀ Back to MAPK3

MAPK3 — REG1A

Text-mined interactions from Literome

Zúñiga et al., J Biol Chem 1999 : Our results demonstrate that the noncatalytic region of PTP-SL associates with mitogen activated protein kinases with high affinity and specificity, providing a mechanism for substrate specificity, and suggest a role for PTP-SL in the regulation of mitogen activated protein kinase translocation to the nucleus upon activation
Patel et al., Front Neuroendocrinol 1999 : The five receptors share common signaling pathways such as the inhibition of adenylyl cyclase, activation of phosphotyrosine phosphatase (PTP) , and modulation of mitogen activated protein kinase ( MAPK ) through G-protein dependent mechanisms ... Four of the receptors ( SSTR1, 2, 4, and 5 ) induce cell cycle arrest via PTP dependent modulation of MAPK , associated with induction of the retinoblastoma tumor suppressor protein and p21
Wu et al., J Clin Endocrinol Metab 1997 : Consistent with the interpretation that the effect of fluoride on the steady state tyrosyl phosphorylation level of p44mapk is a consequence of an inhibition of a phosphotyrosyl phosphatase (PTP) , mitogenic doses of orthovanadate, a bone cell mitogen and a PTP inhibitor, also increased the steady state tyrosyl phosphorylation level of p44mapk, but not p42mapk, in a time dependent sustained manner similar to that observed with fluoride ... Together, these findings support the concept that inhibition of a PTP activity in bone cells could lead to an activation of MAPK activity