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CXCR4 — RHOA

Text-mined interactions from Literome

Badr et al., PloS one 2011 (Multiple Myeloma) : Activation of CXCR4 by CXCL12 resulted in the association of CXCR4 with CD45 and activation of PLCß3, AKT, RhoA , I?Ba and ERK1/2
Badr et al., PloS one 2012 (Multiple Myeloma) : We found that WEV and WEV+NP clearly decreased the CXCL12/CXCR4 mediated activation of AKT, ERK, NF?B and Rho-A using western blot analysis ; abrogated the CXCL12 mediated proliferation of MM cells using the CFSE assay ; and induced apoptosis in MM cell as determined by PI/annexin V double staining followed by flow cytometry analysis