He et al., J Biol Chem 2010
(MAP Kinase Signaling System) :
TGF-beta1 stimulated beta-catenin activation in tubular epithelial cells, and ectopic expression of beta-catenin induced PAI-1 expression, whereas inhibition of beta-catenin abolished its induction ... Deletion or site directed mutation of this site abolished PAI-1 response to beta-catenin or TGF-beta1 stimulation
Di et al., FEBS Lett 2010
:
However, uPA-PAI-1 complex, increased type II VLDLR expression with promoted cell proliferation and migration and stabilization of beta-catenin