Gene interactions and pathways from curated databases and text-mining

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EGFR — SP3

Text-mined interactions from Literome

Xu et al., Cancer Res 2007 (Brain Neoplasms...) : Furthermore, Sp1/Sp3 binding to this site in the promoter is enhanced by EGFR activation both in vitro and in vivo
Chadalapaka et al., Mol Cancer Res 2010 (Urinary Bladder Neoplasms) : EGFR, a putative Sp-regulated gene, was also decreased in cells transfected with a cocktail ( iSp ) containing small inhibitory RNAs for Sp1, Sp3, and Sp4, and RNA interference with individual Sp knockdown indicated that EGFR expression was primarily regulated by Sp1 and Sp3