Gene interactions and pathways from curated databases and text-mining

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MAPK4 — SULT1E1

Text-mined interactions from Literome

Elion et al., J Cell Sci 2001 (MAP Kinase Signaling System) : Early work demonstrated that Ste5p selectively tethers the MAPKKK, MAPKK and MAPK of the yeast mating pathway and is essential for efficient activation of the MAPK by the pheromone stimulus
Flatauer et al., Mol Cell Biol 2005 (MAP Kinase Signaling System) : In contrast to Fus3, the Kss1 MAPK did not require Ste5 scaffolding to receive either authentic or leaking signals
Mitchell et al., Toxicol Lett 2010 (MAP Kinase Signaling System) : To further our understanding of this injury process, the effect of reference moist smokeless tobacco extract (STE) on cell death, oxidative stress, and MAPK signaling in a human oral keratinocyte cell line, HOK-16B, was investigated
Garrenton et al., Proc Natl Acad Sci U S A 2010 (MAP Kinase Signaling System) : Maintenance of this strikingly anisotropic distribution of PtdIns ( 4,5 ) P ( 2 ), stable tethering of Ste5 at the shmoo tip, downstream MAPK activation , and expression of a mating pathway-specific reporter gene all require continuous function of the plasma membrane associated PtdIns 4-kinase Stt4 and the plasma membrane associated PtdIns4P 5-kinase Mss4 ( but not the Golgi associated PtdIns 4-kinase Pik1 )