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ILK — TCF19

Text-mined interactions from Literome

Tan et al., Oncogene 2001 (Adenomatous Polyposis Coli...) : In all cases, inhibition of ILK resulted in substantial inhibition of TCF mediated gene transcription and inhibition of transcription and expression of the TCF regulated gene, cyclin D1 ... These data demonstrate that ILK can regulate beta-catenin/TCF and snail transcription factors by distinct pathways
Oloumi et al., Biochim Biophys Acta 2004 : More specifically, pathological overexpression of ILK results in down-regulation of E-cadherin expression, and nuclear accumulation of beta-catenin, leading to the subsequent activation of the beta-catenin/Tcf transcription complex, the downstream components of the Wnt signalling pathway