Gene interactions and pathways from curated databases and text-mining

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TCF7L1 — WNT1

Text-mined interactions from Literome

Hikasa et al., J Biol Chem 2011 : We also find that TCF3 phosphorylation is triggered by canonical Wnt ligands, LRP6, and dominant negative mutants for Axin and GSK3, indicating that this process shares the same upstream regulators with ß-catenin stabilization
Yi et al., Nat Cell Biol 2011 : Interestingly, both Tcf3-ß-catenin and Tcf1-ß-catenin interactions contributed to Wnt stimulation of self-renewal and gene expression, and the combination of Tcf3 and Tcf1 recruited Wnt stabilized ß-catenin to Oct4 binding sites on ESC chromatin