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IL2 — THY1
Text-mined interactions from Literome
Bellio et al., FASEB J 1999
:
Purified GIPLs from T. cruzi strains Y and G markedly increased IL-2 mRNA transcripts and
IL-2 secretion
induced by mitogenic anti-CD3 and
anti-Thy1 mAbs
Haeryfar et al., J Immunol 2003
:
Cross linking of the GPI anchored protein
Thy-1 results in T cell proliferation and
IL-2 synthesis ... Dendritic cells dramatically enhanced T cell proliferation and
IL-2 synthesis in
response to
Thy-1 triggering by anti-Thy-1 mAb
Lemoine et al., J Gene Med 2004
:
Over 96 % of these
OKT3/IL-2 activated
CD90 ( + ) -selected T-cells were killed by ganciclovir
Haeryfar et al., Immunol Cell Biol 2005
:
Interleukin-2 synthesis and CD25 expression were also
impaired by
Thy-1 blockade
Bellio et al., Cell Immunol 1991
:
Coimmobilized
anti-Thy 1 potently
blocked IL2 secretion stimulated by anti-CD3
Conrad et al., Cell Signal 2009
:
Pharmacologic inhibition of ERK1/2 or JNK activation inhibited
Thy-1 induced DNA synthesis and
IL-2 production by T-lymphocytes
Pont et al., Eur J Immunol 1985
:
Cross linking of cell bound rat mAb by a BALB/c anti-rat kappa chain mAb, or the presence of B cell lymphomas in the culture resulted in an increase of the
Thy-1 mediated
IL2 responses of this hybridoma
Hollander et al., J Immunol 1987
:
Cross linking of the
Thy-1 molecule
resulted in
IL 2 production by the EL4 thymoma and by a T cell hybridoma, suggesting that Thy-1 may play a role in T lymphocyte triggering
Tentori et al., J Immunol 1988
:
IL-2 production
induced by CD3- and
Thy-1 induced activation of fetal thymocytes is evident at the 13th day of gestation
Trial et al., Lymphokine Res 1986
:
Human
interleukin 2 (IL-2) induced the increased expression of I-J and
Thy-1 but not H-2 class I antigens
Gunter et al., Nature 1987
:
The only defect in these variant cell lines responsible for the inability to produce
IL-2 in
response to
Thy-1 stimulation was in the expression of the CD3/Ti complex, because replacement of defective Ti alpha- or beta-chain genes reconstributed both surface expression of CD3/Ti and responsiveness to Thy-1 in the IL-2 production assay
Wiranowska et al., Thymus 1987
:
We have recently found that
interleukin-2 will also
induce Thy 1.2
Shimizu et al., J Immunol 1982
(Lymphoma) :
Anti-T-200 monoclonal antibody inhibited
anti-Thy-1 induced
TCGF production by EL-4 G12 and accessory cells ... The data suggest there are at least 2 different accessory cell help mechanisms in
anti-Thy-1 induced
TCGF production, anti-Thy-1 bound membrane aggregation either by GaRIG, Protein A or FcR, and a LAF dependent mechanism