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TLR3 — VEGFA

Text-mined interactions from Literome

Cho et al., Immunol Lett 2007 (Arthritis, Rheumatoid) : Thus, TLR-2 activation in RA FLS by microbial constituents could be involved in the induction of VEGF and IL-8 and thereby promote inflammation either directly or via angiogenesis
Koff et al., Am J Physiol Lung Cell Mol Physiol 2008 : We conclude that multiple TLR ligands induce airway epithelial cell production of IL-8 and VEGF via a Duox1 -- > ROS -- > TACE -- > TGF-alpha -- > EGFR phosphorylation pathway
Grinberg et al., Am J Pathol 2009 (Inflammation) : This switch involves induction of A ( 2A ) Rs by TLR agonists, down-regulation of tumor necrosis factor alpha (TNFalpha) and interleukin-12, and up-regulation of vascular endothelial growth factor ( VEGF ) and interleukin-10 expression
Spirig et al., PloS one 2010 : In addition, we could show that TLR stimulation resulted in an increase of HIF-1alpha controlled VEGF secretion
Moon et al., Korean J Intern Med 2010 (Arthritis, Rheumatoid...) : Engagement of toll-like receptor 3 induces vascular endothelial growth factor and interleukin-8 in human rheumatoid synovial fibroblasts
Merkle et al., Mol Cell Biochem 2012 : We hereby show a TLR3 mediated upregulation of VEGF and its receptor subtype 2 ( VEGF-R2 ) in human MC upon activation of viral receptors by poly ( I:C ) and hepatitis C virus
He et al., Bing Du Xue Bao 2012 (Dengue...) : These results demonstrated that DENV induced VEGF expression in monocytes, and the activation of TLR3 , IPS-1 signal pathways were required for DENV2 triggered VEGF induction, suggesting that VEGF might be a promising therapeutic target for DHF