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TNF — TPO

Text-mined interactions from Literome

Lu et al., J Hematother Stem Cell Res 2000 : In the presence of IL-11, IL-3, SLF, and Tpo , CFU-MK derived from CB, mPBL, and BM was suppressed by tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta1 ( TGF-beta1 )
Tang et al., Endocrinology 1995 : In the present study, we used FRTL5 cells, a cultured rat thyroid follicular cell line, to examine the effects of IFN-gamma and TNF-alpha on type I 5'-deiodinase ( 5'D-I ) activity and 5'D-I, thyroid peroxidase (TPO) and thyroglobulin (Tg) gene expression ... We also examined the effect of IFN-gamma and TNF-alpha on TPO and Tg gene expression ... As observed with 5'D-I mRNA levels, there was a synergistic effect of IFN-gamma and TNF-alpha on the inhibition of basal and TSH stimulated TPO and Tg gene expression