Gene interactions and pathways from curated databases and text-mining

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RELA — TNFRSF11B

Text-mined interactions from Literome

Min et al., J Exp Med 2000 (Calcinosis...) : Although OPG is normally expressed in arteries, OPG ligand (OPGL) and receptor activator of NF-kappaB ( RANK ) are not detected in the arterial walls of wild-type adult mice
Van Bezooijen et al., Bone 2001 (Bone Resorption) : To further examine the pathway by which osteoclastic resorption was stimulated, we used osteoprotegerin , a specific inhibitor of the receptor activator of NF-kappaB ( RANK ) /receptor activator of the NF-kappaB ligand ( RANKL ) pathway
Kobayashi-Sakamoto et al., Biochem Biophys Res Commun 2004 : NF-kappaB dependent induction of osteoprotegerin by Porphyromonas gingivalis in endothelial cells ... P. gingivalis induced NF-kappaB activation, and the induction of OPG in HMVEC by the pathogen was blocked by the inhibitors of NF-kappaB
Zheng et al., J Biol Chem 2006 (Bone Resorption) : This response was time- and dose dependent, required NF-kappaB activation and new protein synthesis, and was specifically blocked by the RANKL decoy receptor osteoprotegerin
Nakamichi et al., J Immunol 2007 (Bone Resorption) : Osteoprotegerin reduces the serum level of receptor activator of NF-kappaB ligand derived from osteoblasts
Lambert et al., J Bone Miner Res 2007 : In contrast, NF-kappaB was not essential for IL-1beta induction of OPG
Reid et al., Molecular cancer 2009 (Breast Neoplasms...) : These increases in endothelial cell OPG secretion were dependent on alphanubeta3 ligation and NFkappaB activation