Gene interactions and pathways from curated databases and text-mining

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CASP16 — TRAF3

Text-mined interactions from Literome

Lee et al., J Leukoc Biol 2001 : The Fas- or CD3 induced cleavage of TRAF3 was blocked by caspase inhibitors and by introduction of alanine substitutions for D347 and D367 residues
Conti et al., J Neurosurg 2005 (Brain Neoplasms...) : The authors investigated the expression of NF-kappaB, caspase 3, TRAF1, TRAF2, and TRAF associated NF-kappaB activator/TRAF interacting protein ( TANK/I-TRAF ), a regulator of TRAF activity, in human gliomas
Georgopoulos et al., Cell Death Differ 2006 (Urologic Neoplasms) : Thus, TRAF3 stabilization, JNK activation and caspase-9 induction define a novel pathway of CD40 mediated apoptosis in carcinoma cells ... Thus, TRAF3 stabilization, JNK activation and caspase-9 induction define a novel pathway of CD40 mediated apoptosis in carcinoma cells