Gene interactions and pathways from curated databases and text-mining

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CREB1 — TRPC6

Text-mined interactions from Literome

Tai et al., J Cell Sci 2008 (Calcium Signaling) : Downregulation of TRPC6 by short hairpin RNA interference against TRPC6 suppressed phosphorylation of both CaMKIV and CREB and impaired dendritic growth
Yao et al., Mol Med Report 2013 : Our results clearly showed that ICV injection of NPD1 at 2 h after reperfusion improves the neurological status of middle cerebral artery occlusion ( MCAO ) rats through the inhibition of calpain-mediated TRPC6 proteolysis and the subsequent activation of CREB via the Ras/MEK/ERK pathway