Gene interactions and pathways from curated databases and text-mining

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TNF — UCN

Text-mined interactions from Literome

Honjo et al., J Vasc Res 2006 : Tumor necrosis factor-alpha and interferon-gamma increased the urocortin mRNA levels and its release from HUVECs
Ikeda et al., J Mol Endocrinol 2009 (Inflammation) : Ucn I mRNA levels were shown to be up-regulated by lipopolysaccarides (LPS), tumor necrosis factor-alpha (TNF-alpha), Ang II, H ( 2 ) O ( 2 ), and pyrrolidinedithiocarbamate ( PDTC ) ... In addition, the secretion of Ucn I from HL-1 cardiomyocytes was stimulated by LPS and TNF-alpha
Agnello et al., Am J Physiol 1998 : In mice, UCN ( 1 microg/mouse sc ) significantly reduced lipopolysaccharide (LPS) induced serum tumor necrosis factor (TNF) and interleukin (IL)-1beta levels in vivo but did not affect serum IL-6