Gene interactions and pathways from curated databases and text-mining

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RAD21 — VEGFA

Text-mined interactions from Literome

Mabuchi et al., Clin Cancer Res 2007 (Ovarian Neoplasms) : RAD001 also attenuated the expression of HIF-1 alpha and vascular endothelial growth factor , important factors in angiogenesis and tumor invasiveness
Lane et al., Clin Cancer Res 2009 (Neoplasms, Experimental...) : In vivo, in tumor models derived from either sensitive or insensitive cells, RAD001 reduced Tie-2 levels, the amount of mature and immature vessels, total plasma, and tumor VEGF
Cho et al., Acta Biomater 2012 (Diabetes Complications...) : RAD16-II stimulated spontaneous capillary morphogenesis, and increased ß ( 3 ) integrin phosphorylation and VEGF expression in MVECs