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CDH1 — ZEB2
Text-mined interactions from Literome
Alpatov et al., Mol Cell Biol 2004
:
Nuclear speckle associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves
CtBP mediated repression of the
E-cadherin gene
Krishnamachary et al., Cancer Res 2006
(Carcinoma, Renal Cell...) :
Hypoxia-inducible factor-1 dependent repression of
E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma
mediated by TCF3, ZFHX1A, and
ZFHX1B
Verstappen et al., Hum Mol Genet 2008
(Abnormalities, Multiple...) :
We further demonstrate that the NuRD component Mi-2beta is involved in repression of the Zfhx1b target gene
E-cadherin as well as in
Zfhx1b induced neural
induction in animal caps from Xenopus embryos
Korpal et al., J Biol Chem 2008
(Neoplasm Metastasis...) :
These results suggested that loss of expression of the miR-200 family members may play a critical role in the
repression of
E-cadherin by ZEB1 and
ZEB2 during EMT, thereby enhancing migration and invasion during cancer progression
Wang et al., Diabetes 2010
(Fibrosis) :
These data demonstrate the linking
role of miRNA-192/215 and
ZEB2 in TGF-beta/CTGF mediated changes in
E-cadherin expression
Oztas et al., Exp Mol Pathol 2010
(Neoplasms) :
Smad interacting protein 1 ( SIP1, also known as ZEB2 )
represses the transcription of
E-cadherin and mediates epithelial-mesenchymal transition in development and tumor metastasis
Wu et al., Gynecol Oncol 2011
(Neoplasm Invasiveness...) :
Our results suggest that loss of expression of miR-200a may play a critical role in the
repression of
E-cadherin by
ZEB2 , thereby enhancing migration and invasion in CD133/1+ cells
Koopmansch et al., Biochem Biophys Res Commun 2013
:
E-cadherin expression is
repressed by
ZEB2/SIP1 while it is induced by KLF4