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IL10 — ZFP36

Text-mined interactions from Literome

Stoecklin et al., J Biol Chem 2008 (Inflammation) : We further show that IL-10 is a novel target regulated by TTP
Tudor et al., FEBS Lett 2009 (MAP Kinase Signaling System) : TTP directly controls IL-10 mRNA stability, which is increased and insensitive to inhibition of p38 MAPK in TTP ( -/- ) macrophages
Schaljo et al., J Immunol 2009 (Inflammation) : We found that IL-10 initiates a Stat3 dependent increase of TTP expression accompanied by a delayed decrease of p38 MAPK activity
Qin et al., Nutrition 2012 (MAP Kinase Signaling System) : Ex vivo, the CE significantly decreased the amount of apolipoprotein-B48 secretion into the media, inhibited the mRNA expression of genes of the inflammatory cytokines, interleukin-1ß , interleukin-6, and tumor necrosis factor-a, and induced the expression of the anti-inflammatory gene, Zfp36
Gaba et al., J Immunol 2012 : Expression of IL-10 is regulated posttranscriptionally by the RNA binding protein tristetraprolin (TTP) , which destabilizes IL-10 mRNA in activated macrophages ... Correspondingly, STAT3 was required for efficient IL-10 induced TTP expression