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PRKAA1 — ZGLP1
Text-mined interactions from Literome
Huisamen et al., Cardiovasc J S Afr 2008
(Disease Models, Animal...) :
GLP-1 could not directly activate protein kinase B ( also called Akt ) or the extracellular regulated kinases Erk1/2 in hearts or cardiocytes under normoxic conditions, but phosphorylation of the
AMP activated kinase (AMPK) on Thr ( 172 ) was
enhanced
Hurtado-Carneiro et al., Mol Neurobiol 2012
:
Therefore, we investigated the coordinated
effects of glucose and
GLP-1 on the expression and activity of
AMPK and p70S6K in the areas involved in the control of feeding ... The
effect of
GLP-1 on the expression and activities of
AMPK and p70S6K was studied in hypothalamic slice explants exposed to low- and high-glucose concentrations by quantitative real-time RT-PCR and by the quantification of active phosphorylated protein levels by immunoblot
Moberly et al., Basic Res Cardiol 2013
(Diabetes Mellitus, Type 2...) :
No evidence for
GLP-1 mediated
activation of cAMP/PKA or
AMPK signaling in lean or obese hearts was observed