Gene interactions and pathways from curated databases and text-mining
IL6: top 25 interacting genes (chr7:22766765-22771621)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-IL6 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with IL6, not among the Top 25
Other genes interacting with IL6. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

A2M ABCA4 ABCB1 ABCC1 ABCG2 ABL1 ACAN
ACD ACE ACE2 ACHE ACP2 ACR ACSM3
AD5 ADAM17 ADCY1 ADCY10 ADCY2 ADCY3 ADCY4
ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCYAP1 ADH4
ADH5 ADH6 ADH7 ADIPOQ ADIPOR1 ADM ADORA1
ADORA3 AGT AGTR1 AGTR2 AHR AHSA1 AHSG
AIF1 AKT1 AKT2 AKT3 ALB ALG1 AMELX
ANG ANGPT1 ANGPT2 ANGPT4 ANPEP ANXA1 ANXA6
APC APCS APOA4 APOB APOE APP AR
AREG ARG1 ARG2 ARID4B ARSA ASIP ATF1
ATF3 ATF4 ATP5O ATP7A ATP8A2 AVP AZU1
BAI1 BAI2 BAI3 BAX BCL10 BCL2 BCL3
BCL5 BCL6 BCL9 BCR BDNF BGLAP BLVRB
BMP1 BMP10 BMP15 BMP2 BMP3 BMP4 BMP5
BMP6 BMP7 BPI BSG BTK BTRC C1QA
C1QB C1orf228 C3AR1 C4BPA C5 C5AR1 CA1
CA2 CALCA CALM1 CALM2 CALM3 CALML3 CASP1
CASP10 CASP12 CASP14 CASP16 CASP2 CASP3 CASP4
CASP5 CASP6 CASP7 CASP8 CASP9 CAT CAV1
CAV2 CAV3 CBL CCK CCL1 CCL2 CCL20
CCL3 CCL4 CCL5 CCND1 CCR1 CCR2 CCR5
CCR6 CD14 CD163 CD19 CD1C CD1D CD2
CD274 CD28 CD33 CD34 CD38 CD4 CD40
CD40LG CD44 CD46 CD5 CD59 CD69 CD79A
CD80 CD86 CD8A CD8B CDC73 CDH1 CDK4
CDK9 CDKN1A CDKN1B CDKN2A CEACAM1 CEACAM5 CEBPA
CEBPB CEBPD CEBPZ CHAT CHGA CHP1 CHP2
CHUK CIB1 CISH CLEC7A CLU CNR2 CNTF
CNTN2 COL1A1 COQ2 COQ3 COQ4 COQ5 COQ6
COQ7 COQ9 CORT CP CPA1 CPB1 CPB2
CPOX CR2 CRAT CREB1 CREB3 CREB5 CREBBP
CRH CRK CRP CRYGEP CSE CSF1 CSF2
CSF3 CSH2 CSK CSRP1 CTF1 CTGF CTR9
CTSB CTSL CTSS CUL1 CX3CL1 CX3CR1 CXCL1
CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL16 CXCL17
CXCL2 CXCL3 CXCL5 CXCL6 CXCL9 CXCR3 CXCR4
CYP19A1 CYP1A1 CYP1A2 CYP3A CYP3A4 DDIT3 DEFB114
DEFB4B DERL1 DNMT1 DUSP1 DYNLRB1 E2F1 EBP
ECM1 ECM2 EDN1 EDN2 EDN3 EDNRA EEF1A2
EGF EGFR EGR1 EIF2AK2 EPHB2 EPO EPS15
EPS8 EPX ERBB3 EREG ERVK-6 ESR1 ESR2
ETS1 ETS2 F12 F2R F2RL1 FAS FASLG
FCER2 FCGR1A FGB FGF1 FGF10 FGF11 FGF12
FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2
FGF20 FGF21 FGF22 FGF23 FGF3 FGF4 FGF5
FGF6 FGF7 FGF8 FGF9 FGFR2 FGFR3 FGL1
FLOT2 FLT3LG FMR1 FOS FOXO1 FOXO3 FOXP3
FUT4 FXR1 FXR2 FXYD1 FYN GAL GAS6
GAST GCG GCLC GCSAM GFAP GH1 GHRH
GIF GIP GNA13 GNRH1 GP2 GP5 GP6
GP9 GPI GPX1 GPX2 GPX3 GPX4 GPX5
GPX6 GPX7 GPX8 GRAP2 GRB2 GSTM1 GSTM2
GSTM3 GSTM4 GSTM5 GTF2B GYS1 GYS2 GZMB
HAMP HBD HCFC1 HCK HCL1 HCL2 HCL3
HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5
HDAC6 HDAC7 HDAC8 HDAC9 HDC HES1 HES2
HES3 HES4 HES5 HES6 HES7 HGF HIF1A
HLA-DRA HLA-DRB1 HMGB1 HMGCR HMOX1 HNRNPA1 HNRNPF
HNRNPH1 HP HPD HPX HRAS HSF1 HSP90AA1
HSP90AB1 HSPA5 HSPB1 HSPB3 HSPB8 HSPD1 HSPG2
IBD2 IBD3 IBD4 IBD5 IBD6 IBD7 IBD8
IBD9 ICAM1 ICAM2 ICAM3 ICAM4 ICAM5 ICOS
ICOSLG IDO1 IDS IFI27 IFI44 IFIT1 IFNA1
IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21
IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB1 IGF1
IGF1R IGF2 IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5
IGFBP7 IKBKB IKBKG IL11 IL12A IL12B IL13
IL15 IL16 IL17A IL17D IL17F IL17RA IL18
IL19 IL1R1 IL1R2 IL1RAP IL1RN IL20 IL21
IL22 IL23A IL24 IL25 IL26 IL27 IL2RA
IL2RB IL2RG IL3 IL31 IL32 IL33 IL34
IL37 IL5 IL6R IL6ST IL7 IL9 INA
INS IRAK1 IRAK2 IRAK3 IRAK4 IRF1 IRF2
IRF3 IRF4 IRF5 IRF7 IRF8 IRF9 IRG1
IRS1 ITGA2B ITGA4 ITGA5 ITGAM ITGB1 ITIH4
JAK1 JAK2 JAK3 JUN JUNB JUND KAT2B
KDR KITLG KLK3 KLRB1 KNG1 KRT10 KRT13
KRT37 KRT38 LBP LCAT LCN2 LDLR LEO1
LEP LGALS1 LGALS3 LIF LPA LPL LRG1
LRPPRC LTA LTB LTF LYN LYZ MAF
MAL MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6
MAP2K7 MAP3K3 MAP3K7 MAPK4 MAPKAPK2 MBP MCC
MCL1 MCS MEOX2 MEPE MET MIA MICE
MIF MIP MKL1 MMP1 MMP10 MMP11 MMP12
MMP13 MMP14 MMP15 MMP16 MMP17 MMP19 MMP2
MMP20 MMP21 MMP24 MMP25 MMP26 MMP27 MMP28
MMP3 MMP7 MMP8 MMP9 MOG MPG MPL
MPO MRXS5 MS4A1 MSC MSH2 MSH3 MSH4
MSH5 MSH6 MT3 MT4 MTA1 MTA2 MTA3
MTOR MTX1 MUC1 MUC12 MUC13 MUC15 MUC16
MUC17 MUC19 MUC2 MUC20 MUC21 MUC22 MUC4
MUC5AC MUC6 MUC7 MUC8 MYC MYD88 MYLIP
MYO10 MYO16 MYO19 MYO6 NA NAALADL1 NAMPT
NANOG NCAM1 NDP NEUROD1 NEUROD2 NEUROD4 NEUROD6
NFATC2 NFKB2 NFKBIA NGF NLRC5 NLRP3 NM
NMU NNMT NOD1 NOD2 NOS1 NOS2 NOS3
NOTCH1 NOTCH2 NOX1 NOX3 NOX4 NOX5 NPEPPS
NPPA NPS NPY NPY4R NR0B1 NR4A1 NT5E
NTF3 NTF4 NTN1 NTS NUP43 OAS1 OAS2
OAS3 OPN1LW OPRM1 OSM OXA1L OXTR P2RX1
P2RX7 P2RY6 PAEP PAF1 PAM PARK2 PARK7
PARP1 PARP10 PARP11 PARP12 PARP14 PARP15 PARP16
PARP2 PARP3 PARP4 PARP6 PARP8 PARP9 PC
PCK1 PCK2 PDAP1 PDCD1 PDCD10 PDCD11 PDCD2
PDCD4 PDCD5 PDCD6 PDCD7 PDGFA PDGFB PDLIM7
PGD PGF PGP PHB PI3 PIAS1 PIAS3
PIGA PIK3C3 PIK3CA PIK3R1 PIM1 PINK1 PITX2
PLA2G1B PLA2G2D PLA2G4A PLAT PLD1 PLD2 PLD3
PLD4 PLD5 PLD6 PLG POLDIP2 POMC PON1
POU5F1 PPARA PPARG PPP2CA PPP2R1A PPP2R2B PPP5C
PRDX2 PRG2 PRG3 PRG4 PRKAA1 PRKAA2 PRKAB1
PRKAB2 PRKACB PRKACG PRKAG1 PRKAG2 PRKAR1A PRKAR1B
PRKAR2A PRKAR2B PRKCA PRKD1 PRL PRNP PSMB9
PTBP1 PTBP2 PTGER4 PTGS1 PTGS2 PTH PTHLH
PTK2 PTK2B PTK6 PTK7 PTPN11 PTPN22 PTPN4
PTPRC PTPRE PTS PTX3 PTX4 QRICH1 QRICH2
RAB7A RAB7B RABEPK RAC1 RAF1 RAG1 RAG2
RASIP1 RB1 RBBP4 RBBP7 RBP4 REG1A REL
REN RENBP RETN RHO RLN1 RLN2 RLN3
RNASE3 RNF19A ROR1 ROR2 RORC RPL17 RPS6KA3
RUNX2 S100A12 S100A8 S100A9 S100B SAA1 SAA2
SAA3P SAA4 SAP130 SAP30 SARS SCARB1 SCG2
SCG3 SCG5 SDC1 SEA SELE SELL SELP
SERPINA1 SERPINA3 SERPINA6 SERPINB5 SERPINE1 SERPINE2 SERPINF1
SERPING1 SETBP1 SETD2 SFTPA1 SFTPC SH3GL2 SHC1
SIN3A SKP1 SLC25A3 SLC33A1 SLC39A14 SLPI SMAD1
SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMAD7 SMAD9
SMC2 SMC3 SMC4 SMC5 SMC6 SMN1 SOAT1
SOCS1 SOCS3 SOD1 SOD2 SOD3 SOS1 SP1
SP3 SPN SPP1 SRC SST ST2 STAT1
STAT4 STAT5A STEAP4 STK10 STK11 STK16 STK19
STK24 STK25 STK3 STK31 STK33 STK35 STK36
STK38 STK39 STK4 STK40 STS SUDS3 SYK
SYT1 TAB1 TAC1 TAC3 TAC4 TAT TBCC
TBP TCF12 TCF15 TCF19 TCF20 TCF21 TCF23
TCF24 TCF25 TCF3 TCF4 TCF7 TEC TF
TFAP2A TFPI TGFA TGFB1 TGFB2 TGFB3 TGM2
TGM4 TGM7 THBD THBS1 TIMP1 TIMP2 TIMP3
TIRAP TLR1 TLR10 TLR2 TLR3 TLR4 TLR5
TLR6 TLR7 TLR8 TLR9 TNC TNFAIP6 TNFRSF11B
TNFRSF1A TNFRSF1B TNFRSF8 TNFSF10 TNFSF11 TNFSF13B TNPO1
TP53 TPO TRAF1 TRAF2 TRAF3IP2 TRAF5 TRAF6
TRD TRNAI1 TRPV1 TSC22D3 TSLP TSN TTR
TXN TYK2 TYR UCN UCN2 UCN3 UTP15
UTP18 UTP20 UTP23 UTP3 UTP6 VAV1 VCAM1
VCP VEGFA VHLL VIMP VIP VWF WAS
WDR61 WNK1 WNT1 WNT10B WNT11 WNT16 WNT2
WNT3 WNT4 WNT5A WNT6 XBP1 XIAP XRCC1
ZBTB16 ZFP36
Data information
Please see the Gene Interactions Track Manual.