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ADAM11 — IFNG
Text-mined interactions from Literome
Horikawa et al., Int Immunol 2002
(Dermatitis, Atopic) :
Furthermore, primary epidermal keratinocytes expressed both TARC and MDC mRNA upon
stimulation with
IFN-gamma , but efficiently secreted only
MDC
Kanda et al., Clin Exp Allergy 2002
(Dermatitis, Atopic...) :
MF
induced IL-4 and
macrophage derived chemokine (MDC) secretion in AD patients, while induced
IFN-gamma and interferon-inducible protein of 10 kDa (IP-10) secretion in PV patients, however, did not induce either secretion in normal subjects
Xiao et al., J Dermatol Sci 2003
:
MDC mRNA was weakly expressed in HaCaT cells, and upon
stimulation with TNF-alpha or
IFN-gamma ,
MDC expression was strongly upregulated
Nasu et al., Fertil Steril 2004
:
The
effects of interleukin (IL)-2, IL-4, IL-5, IL-10, IL-12, IL-13,
interferon-gamma (IFN-gamma) , and tumor necrosis factor-beta (TNF-beta) on the production of TARC and
MDC were investigated
Yamada et al., J Urol 2005
(Urinary Bladder Neoplasms) :
Previously we have reported that RT4, a well differentiated human bladder cancer line, increases the expression of
macrophage derived chemokine (MDC) and interferon (IFN)-gamma-inducible protein-10 ( IP-10 ) in
response to
IFN-gamma and tumor necrosis factor (TNF)-alpha
Yonkers et al., Clin Immunol 2009
(HIV Infections...) :
In purified MDC-NK co-cultures,
MDC dependent NK
IFN-gamma and Granzyme B was intact in both HCV and HIV infections, while MDC numerical defects were observed in HIV infection
Qi et al., Mol Immunol 2009
:
Moreover, inhibition of NF-kappaB suppressed TARC and
MDC production
induced by
IFN-gamma plus TNF-alpha
Qi et al., Br J Pharmacol 2009
:
Fluvastatin inhibits expression of the chemokine
MDC/CCL22 induced by
interferon-gamma in HaCaT cells, a human keratinocyte cell line ... Fluvastatin, but not atorvastatin or simvastatin, inhibited
MDC expression
induced by
interferon (IFN)-gamma and NF-kappaB activation ... Further, inhibition of p38 mitogen activated protein kinases ( MAPKs ) significantly suppressed
IFN-gamma induced
MDC expression and NF-kappaB activation ... These results indicate that fluvastatin inhibited expression of the CC chemokine
MDC induced by
IFN-gamma in HaCaT cells, by inhibiting NF-kappaB activation via the p38 MAPK pathway
Castellaneta et al., J Immunol 2009
:
Following MDP stimulation in vivo, liver pDC, but not
mDC , up-regulated expression of IFN regulatory factor 4 (IRF-4), a negative regulator of TLR signaling, and
induced less allogeneic T cell proliferation and
IFN-gamma production
Bonecchi et al., Blood 1998
:
MDC expression and production induced by IL-4 and IL-13 were
inhibited by
IFN-gamma ...
IFN-gamma also
suppressed the constitutive expression of
MDC in mature macrophages and dendritic cells ... These results delineate an amplification loop of polarized Th2 responses based on differential
regulation of
MDC production by IL-4 and IL-13 versus
IFN-gamma and on the selectivity of this chemokine for polarized Th2 cells