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ADCY3 — NOS2

Text-mined interactions from Literome

Morello et al., Life Sci 2006 : Galangin ( 0.1-100 microM ) induced relaxation in rings pre contracted with phenylephrine ( PE 1 microM ) or with KCl ( 100 mM ) or pre treated with the nitric oxide synthase inhibitor Nomega-nitro-L-arginine methyl ester ( L-NAME, 100 microM ), the cyclooxygenase inhibitor indomethacin ( 10 microM ) and the adenylate cyclase inhibitor , SQ 22,536 ( 100 microM )
Tetsuka et al., Proc Natl Acad Sci U S A 1994 : These data suggest that ( i ) endogenous PGE2 downregulates iNOS induction, ( ii ) this inhibitory effect of PGE2 on iNOS induction is not mediated by activation of adenylate cyclase , and ( iii ) exogenous PGI2 stimulates COX induction possibly by activation of adenylate cyclase