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AKAP13 — NFKB1

Text-mined interactions from Literome

Sakai et al., J Biochem 2001 : Receptor activator of NF-kappaB ( RANKL ) significantly increased the LBC levels of cathepsin K, TRAP, and c-Src, whereas calcitonin decreased the LBC levels of cathepsin K, TRAP, and Rab7, indicating that the transformation of early to late endosomal elements and lysosomes in OCLs is also regulated by osteoclastogenesis regulatory factors
Shibolet et al., J Biol Chem 2007 : By systematically integrating expression profiles from immune and epithelial cells with functional studies, we demonstrate that protein kinase A anchoring protein 13 ( AKAP13 ), a scaffold protein with GEF activity, is an activator of NF-kappaB downstream of TLR2 signaling ... Furthermore, NF-kappaB activation was partially inhibited by a GEF-deficient AKAP13 mutant ... Together, our results suggest that AKAP13 plays a role in TLR2 mediated NF-kappaB activation and suggest that GEF containing scaffold proteins may confer specificity to innate immune responses downstream of TLRs