Gene interactions and pathways from curated databases and text-mining

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ANGPT1 — IL8

Text-mined interactions from Literome

Pizurki et al., Br J Pharmacol 2003 : Angiopoietin-1 inhibits endothelial permeability, neutrophil adherence and IL-8 production
Abdel-Malak et al., Blood 2008 : Ang-1 elicited in human umbilical vein endothelial cells ( HUVECs ) a dose- and time dependent increase in IL-8 production as a result of induction of mRNA and enhanced mRNA stability of IL-8 transcripts ... Upstream from the AP-1 complex, up-regulation of IL-8 transcription by Ang-1 was mediated through the Erk1/2, SAPK/JNK, and PI-3 kinase pathways, which triggered c-Jun phosphorylation on Ser63 and Ser73
Choe et al., Joint Bone Spine 2012 (Arthritis, Rheumatoid...) : Tacrolimus ( FK506 ) inhibits interleukin-1ß induced angiopoietin-1 , Tie-2 receptor, and vascular endothelial growth factor through down-regulation of JNK and p38 pathway in human rheumatoid fibroblast-like synoviocytes
Neagoe et al., J Cell Physiol 2012 : Angiopoietin-1 but not angiopoietin-2 induces IL-8 synthesis and release by human neutrophils