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APCS — IFNG

Text-mined interactions from Literome

Walravens et al., Vet Immunol Immunopathol 2002 (Tuberculosis, Bovine) : Magnetic positive selection of T-cells from infected animals showed that CD4+ T-cells produced specific IFN-gamma only in the presence of antigen presenting cells (APCs) ... Positively selected CD8+ T-cells secreted IFN-gamma only in the presence of recombinant human IL-2 and APCs
Pedras-Vasconcelos et al., Infect Immun 2002 (Disease Susceptibility...) : Hyporesponsiveness towards SEB and BCG-Ag in unfractionated splenocyte cultures was not due to suppressive antigen presenting cells (APCs), as APCs from infected mice stimulated higher levels of IFN-gamma from purified T cells
Trembleau et al., J Immunol 2003 (Diabetes Mellitus, Type 1...) : Surprisingly, IL-12 induced IFN-gamma hinders pancreatic B cell infiltration and inhibits the capacity of APCs to activate T cells
Chou et al., J Immunol 2005 (Berylliosis...) : Our results demonstrate that in the presence of APCs , beryllium induced strong proliferation responses of BAL CD4 ( + ) T cells, production of superoptimal concentrations of secreted proinflammatory cytokines, IFN-gamma , TNF-alpha, and IL-2, and up-regulation of numerous T cell surface markers that would promote T-T Ag presentation
Artis et al., J Immunol 2005 : In an in vivo adoptive transfer model in which NF-kappaB-sufficient OVA-specific DO11.10 TCR transgenic T cells were injected into OVA immunized WT or NF-kappaB1 ( -/- ) hosts, NF-kappaB1 ( -/- ) APCs efficiently promoted CD4 ( + ) T cell proliferation and IFN-gamma responses, but failed to promote Ag-specific IL-4 production
Bloch-Queyrat et al., J Exp Med 2005 (Lymphoproliferative Disorders) : In keeping with earlier reports that studied human NK cells, we showed that SAP was necessary for the ability of 2B4 to trigger cytotoxicity and IFN-gamma secretion
Skinner et al., J Immunol 2005 (Bordetella Infections...) : These findings suggest that B. bronchiseptica use the TTSS to rapidly drive respiratory DCs to secondary lymphoid tissues where these APCs stimulate an immunosuppressive response characterized by increased IL-10 and decreased IFN-gamma production that favors bacterial persistence
Park et al., Immunology 2008 : In vitro, GM3 loaded APCs also suppressed the interleukin-4 response, but not the interferon-gamma response, of NKT cells to alpha-galactosylceramide
Taylor et al., Blood 2008 (Graft vs Host Disease) : We show that CpG ODNs markedly accelerated graft-versus-host disease ( GVHD ) lethality by Toll-like receptor 9 (TLR9) ligation of host antigen presenting cells (APCs) , dependent upon host IFNgamma but independent of host IL-12, IL-6, or natural killer ( NK ) cells
Kryczek et al., J Immunol 2008 : Interestingly, IFN-gamma triggers APCs to produce IL-1 and IL-23 and enables them to induce memory Th17 expansion via IL-1 and IL-23 in a B7-H1 independent manner
Nijnik et al., J Immunol 2009 : Human cathelicidin peptide LL-37 modulates the effects of IFN-gamma on APCs
Tanaka et al., Proc Natl Acad Sci U S A 1993 : Nor did IL-4 inhibit production of IFN-gamma by cloned T cells in response to antigen and APCs or production of IL-2 and IFN-gamma by naive T cells in response to phorbol ester and calcium ionophore
Cantorna et al., J Immunol 1996 : The retinol metabolite retinoic acid inhibited the IFN-gamma stimulatory activity of APCs , enhanced Th2 cell differentiation, and inhibited Th1 cell IFN-gamma synthesis
Sad et al., J Immunol 1997 : IL-2 synthesis was the most sensitive, as stimulation of IL-4 treated Tc1 cells with higher numbers of APCs partially restored IFN-gamma , TNF, and IL-10, but not IL-2, synthesis