Gene interactions and pathways from curated databases and text-mining

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ARG2 — TNF

Text-mined interactions from Literome

Moinard et al., J Leukoc Biol 2000 : GLN, ARG , and OKG all restored TNF-alpha secretion by macrophages of glucocorticoid treated rats
Meszaros et al., J Immunol 2000 : Mphi induced apoptosis was inhibited by peptide Arg-Gly-Asp-Ser , anti-beta3 ( CD61 ) Ab, CD36 peptide, or anti-TNF-alpha Ab. Soluble TNF-alpha did not induce PMN apoptosis
Zhang et al., Clin Exp Allergy 2005 (Asthma...) : Actinomycin D abolished and dexamethasone concentration-dependently suppressed the TNF-alpha induced enhancement of the des-Arg9-bradykinin and bradykinin responses
Ckless et al., Am J Respir Cell Mol Biol 2007 : Our results demonstrate that reduction of arginase activity enhanced cellular content of NO and S-nitrosated proteins, and resulted in decreases in TNF-alpha- or LPS stimulated NF-kappaB DNA binding and transcriptional activity, in association with enhanced S-nitrosation of p50
Gao et al., Arterioscler Thromb Vasc Biol 2007 (Disease Models, Animal...) : Our data demonstrate TNF-alpha upregulates expression of arginase in endothelial cells, which leads to O2 ( - ) production then induces endothelial dysfunction in I/R injury
Grenier et al., Toxins 2010 : Both Arg- and Lys-gingipain preparations induced the secretion of TNF-a and IL-8 by macrophages