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BCR — CREB3

Text-mined interactions from Literome

Swart et al., J Immunol 2000 (Lymphoma, B-Cell...) : Inhibition of p38 MAPK by pretreating CH31 B cells with the highly specific bicyclic imidazole inhibitor, SB203580, reduced BCR induced CREB phosphorylation ... The results implicate a p38 MAPK pathway in BCR mediated CREB phosphorylation and junB transcriptional activation in B cell lymphomas
Yokohari et al., Biochem Biophys Res Commun 2001 : Here we show that overexpression of BRDG1 strongly augments BCR mediated activation of cAMP-response element binding protein ( CREB ) but not that of c-Jun and the promoters of c-MYC and BCL-xL genes
Koncz et al., Immunol Lett 2002 : We compared the BCR induced intracellular [ Ca2+ ] transient, protein tyrosine phosphorylation and ERK phosphorylation, furthermore, the activation of Elk-1 and CREB transcription factors
Blois et al., J Biol Chem 2004 : Bryostatin 1 selectively prevents nPKCdelta depletion by phorbol 12-myristate 13-acetate when coapplied, coincident with protection of BCR induced CREB phosphorylation ... Ectopic expression of a kinase-inactive nPKCdelta blocks BCR induced CREB phosphorylation in A20 B cells ... In addition, BCR induced CREB phosphorylation is significantly diminished in nPKCdelta-deficient splenic B cells in comparison with wild type mice ... Taken together, these results suggest a model in which BCR engagement leads to the phosphorylation of CREB via a signaling pathway that requires nPKCdelta and p90 RSK in mature B cells