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BMP4 — SLC22A3
Text-mined interactions from Literome
Thériault et al., Carcinogenesis 2007
(Disease Progression...) :
BMP4 induces
EMT and Rho GTPase activation in human ovarian cancer cells
Okagawa et al., Dev Biol 2007
:
These results provide evidence that
BMP signaling through the AV endocardium is
required for the
EMT and the activation of the BMP receptor in the endocardium can promote AV EMT in the chick
Ohta et al., Development 2007
:
These indicate that the inhibition of
Bmp signaling by temporal and/or spatial Nog expression
suppresses EMT and leads to the cessation of the ingressive cell movement from the VER at the end of gastrulation
Yan et al., Am J Pathol 2010
(Cicatrix...) :
Moreover, TNF-alpha induced EMT was impaired by antagonists against bone morphogen proteins (BMP) 2/4, suggesting that
BMP mediates the TNF-alpha induced
EMT in human skin
Xu et al., Arch Med Res 2011
(Carcinoma...) :
Knockdown of Smad1 expression suppressed
BMP-4 induced
EMT in both cell lines and weakened the invasiveness and migration of Tu686 and Tu212 in vitro
Qiao et al., Oncol Rep 2011
(Carcinoma, Squamous Cell...) :
In this study, we aimed to determine whether
BMP-4 ( bone morphogenetic protein-4 ) could
induce epithelial-mesenchymal transition (EMT) with acquisition of stem cell-like phenotypes in a cell-culture model
Huang et al., Stem cell research 2013
:
Induction of
EMT-like response by
BMP4 via up-regulation of lysyl oxidase is required for adipocyte lineage commitment
Bai et al., Development 2013
(Truncus Arteriosus, Persistent...) :
To directly address the function of Vegfa repression in
Bmp mediated
EMT , we performed ex vivo explant cultures from Bmp4/7 and miR-17-92 mutant hearts