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Text-mined interactions from Literome
Fritz et al., Oncogene 1999
:
Phosphorylation of the DNA repair protein
APE/REF-1 by CKII
affects redox regulation of
AP-1 ... Inhibition of CKII mediated phosphorylation of
APE/Ref-1 blocked mutagen stimulated increase in
AP-1 binding
Robertson et al., Cancer Res 2001
(Carcinoma, Embryonal...) :
Moreover,
Ape1/ref-1 stimulates the DNA binding activity of transcription factors (
Fos-Jun , nuclear factor-kappaB, Myb, ATF/cyclic AMP-responsive element binding protein family, HIF-1alpha, HLF, PAX, and p53 ) through a redox mechanism and thus represents a novel component of signal transduction processes that regulate eukaryotic gene expression