Gene interactions and pathways from curated databases and text-mining

◀ Back to JUN

CCDC88A — JUN

Text-mined interactions from Literome

Fritz et al., Oncogene 1999 : Phosphorylation of the DNA repair protein APE/REF-1 by CKII affects redox regulation of AP-1 ... Inhibition of CKII mediated phosphorylation of APE/Ref-1 blocked mutagen stimulated increase in AP-1 binding
Robertson et al., Cancer Res 2001 (Carcinoma, Embryonal...) : Moreover, Ape1/ref-1 stimulates the DNA binding activity of transcription factors ( Fos-Jun , nuclear factor-kappaB, Myb, ATF/cyclic AMP-responsive element binding protein family, HIF-1alpha, HLF, PAX, and p53 ) through a redox mechanism and thus represents a novel component of signal transduction processes that regulate eukaryotic gene expression