Gene interactions and pathways from curated databases and text-mining

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CCR2 — ICAM1

Text-mined interactions from Literome

Giunti et al., Kidney Int 2006 : This effect occurred via the CCR2 receptor as CCR2 was expressed in HMCs and CCR2 blockade prevented ICAM-1 upregulation
Elmarakby et al., Hypertension 2007 (Hypertension) : Renal tumor necrosis factor-alpha and intercellular adhesion molecule-1 expression increased, and Cyp2c23 expression decreased in ANG/HS hypertension compared with the HS group, and CCR2b inhibition reduced tumor necrosis factor-alpha and intercellular adhesion molecule-1 and increased Cyp2c23 expression