Gene interactions and pathways from curated databases and text-mining

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CD80 — IL13

Text-mined interactions from Literome

Oki et al., Eur J Immunol 2000 : The Stat6 association with CD28 is specifically induced by CD80 or CD86 ligand binding and is not dependent upon the secretion of IL-4 or IL-13
Rafiq et al., Clin Exp Immunol 2000 : In accordance with this, CD80 and phorbol myristate acetate ( PMA ) ( without anti-CD3 or calcium ionophore ) were sufficient to induce production of IL-5 and IL-13 , but not of IL-4
Blanchet et al., Am J Respir Crit Care Med 2004 (Alveolitis, Extrinsic Allergic) : To test the effect of nicotine on alveolar macrophages, AMJ2-C11 cells were treated with nicotine and stimulated with lipopolysaccharide or Saccharopolyspora rectivirgula, a causative agent of HP. Nicotine reduced tumor necrosis factor release and tumor necrosis factor, interleukin-10 , and IFN-gamma mRNA expression after stimulation and decreased CD80 expression by 55 % in lipopolysaccharide stimulated cells and by 41 % in S. rectivirgula stimulated cells
Takizawa et al., Clin Exp Allergy 2007 (Rhinitis) : Next, we examined the effect of IL-1beta, TNF-alpha, ( IFN-gamma ), IL-4 alpha, IL-13 and diesel exhaust particles ( DEP ) on the HLA-DR, CD80 and CD86 expression in cultured nasal epithelial cells ( CNEC ), by flow cytometry
Saw et al., Am J Pathol 2009 (Pemphigoid, Benign Mucous Membrane) : IL-13 also up-regulated surface expression of HLA-DR, CD80 , CD40, and CD154 by conjunctival fibroblasts, suggesting a potential mechanism for fibroblast-T cell cross talk, via which fibroblasts may actively engage in perpetuating chronic inflammation and continued fibrosis