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CD80 — IL13
Text-mined interactions from Literome
Oki et al., Eur J Immunol 2000
:
The Stat6 association with CD28 is specifically induced by
CD80 or CD86 ligand binding and is not
dependent upon the secretion of IL-4 or
IL-13
Rafiq et al., Clin Exp Immunol 2000
:
In accordance with this,
CD80 and phorbol myristate acetate ( PMA ) ( without anti-CD3 or calcium ionophore ) were
sufficient to induce production of IL-5 and
IL-13 , but not of IL-4
Blanchet et al., Am J Respir Crit Care Med 2004
(Alveolitis, Extrinsic Allergic) :
To test the effect of nicotine on alveolar macrophages, AMJ2-C11 cells were treated with nicotine and stimulated with lipopolysaccharide or Saccharopolyspora rectivirgula, a causative agent of HP. Nicotine reduced tumor necrosis factor release and tumor necrosis factor,
interleukin-10 , and IFN-gamma mRNA expression after stimulation and decreased
CD80 expression by 55 % in lipopolysaccharide stimulated cells and by 41 % in S. rectivirgula
stimulated cells
Takizawa et al., Clin Exp Allergy 2007
(Rhinitis) :
Next, we examined the
effect of IL-1beta, TNF-alpha, ( IFN-gamma ), IL-4 alpha,
IL-13 and diesel exhaust particles ( DEP ) on the HLA-DR,
CD80 and CD86 expression in cultured nasal epithelial cells ( CNEC ), by flow cytometry
Saw et al., Am J Pathol 2009
(Pemphigoid, Benign Mucous Membrane) :
IL-13 also
up-regulated surface expression of HLA-DR,
CD80 , CD40, and CD154 by conjunctival fibroblasts, suggesting a potential mechanism for fibroblast-T cell cross talk, via which fibroblasts may actively engage in perpetuating chronic inflammation and continued fibrosis