Gene interactions and pathways from curated databases and text-mining

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AKT1 — CDK1

Text-mined interactions from Literome

Kalous et al., Biol Cell 2006 : It can imply that PKB is also involved in CDK1 activation in mammalian oocytes ... PKB activation was independent of CDK1 activity, because although butyrolactone I prevented CDK1 activation and GVBD, PKB was nevertheless transiently phosphorylated and activated ... The results of the present paper indicate that PKB is involved in CDK1 activation and resumption of meiosis in mouse oocytes
Lee et al., J Cell Physiol 2005 : Expression of myr-Akt also led to an increase in the protein and mRNA levels of CDK1 and cyclin B1
Minelli et al., Peptides 2006 : It greatly enhances the phosphorylation of hsp27, alpha-B-crystallin, Cdc2 , and p-38 MAPK, whereas it decreases the phosphorylation of MEK1, Cav 2, GSK3a, PKB/Akt , PKCdelta, PKCgamma, and Erk2 ... It greatly enhances the phosphorylation of hsp27, alpha-B-crystallin, Cdc2 , and p-38 MAPK, whereas it decreases the phosphorylation of MEK1, Cav 2, GSK3a, PKB/Akt , PKCdelta, PKCgamma, and Erk2
Kalous et al., Reproduction 2009 : Moreover, the activity of the cyclin dependent kinase 1 (CDK1) and MAP kinase declined when SH-6 treated DOs underwent GVBD, indicating that AKT activity is involved in the regulation of CDK1 and MAP kinase
Leonard et al., Cell cycle (Georgetown, Tex.) 2013 : Inhibition of Akt activation with MK2206 reduced the whole-cell and centrosome levels of PLK-1 and ?-tubulin and also prevented the recruitment of PTEN to mitotic centrosomes