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AKT1 — CDK1
Text-mined interactions from Literome
Kalous et al., Biol Cell 2006
:
It can imply that
PKB is also
involved in
CDK1 activation in mammalian oocytes ...
PKB activation was
independent of
CDK1 activity, because although butyrolactone I prevented CDK1 activation and GVBD, PKB was nevertheless transiently phosphorylated and activated ... The results of the present paper indicate that
PKB is
involved in
CDK1 activation and resumption of meiosis in mouse oocytes
Lee et al., J Cell Physiol 2005
:
Expression of
myr-Akt also
led to an increase in the protein and mRNA levels of
CDK1 and cyclin B1
Minelli et al., Peptides 2006
:
It greatly
enhances the phosphorylation of hsp27, alpha-B-crystallin,
Cdc2 , and p-38 MAPK, whereas it decreases the phosphorylation of MEK1, Cav 2, GSK3a,
PKB/Akt , PKCdelta, PKCgamma, and Erk2 ... It greatly
enhances the phosphorylation of hsp27, alpha-B-crystallin,
Cdc2 , and p-38 MAPK, whereas it decreases the phosphorylation of MEK1, Cav 2, GSK3a,
PKB/Akt , PKCdelta, PKCgamma, and Erk2
Kalous et al., Reproduction 2009
:
Moreover, the activity of the cyclin dependent kinase 1 (CDK1) and MAP kinase declined when SH-6 treated DOs underwent GVBD, indicating that
AKT activity is
involved in the regulation of
CDK1 and MAP kinase
Leonard et al., Cell cycle (Georgetown, Tex.) 2013
:
Inhibition of
Akt activation with MK2206
reduced the whole-cell and
centrosome levels of PLK-1 and ?-tubulin and also prevented the recruitment of PTEN to mitotic centrosomes