Gene interactions and pathways from curated databases and text-mining

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CXCR3 — IL15

Text-mined interactions from Literome

Agostini et al., Am J Respir Crit Care Med 2005 (Chronic Disease...) : In vitro kinetic studies demonstrated that, although CXCR3 was rapidly induced by interleukin (IL)-15 and IL-18, CXCR6 induction was slow ( 8 d ) and mainly regulated by IL-15
Schmitz et al., Brain Behav Immun 2013 : Oppositely, CXCR3-deficiency had no protective effect after traumatic nerve injury but reduced EAE evoked hyperalgesia and was associated with reduced clinical EAE scores, a reduction of the pro-inflammatory cell infiltration and reduced upregulation of interferon gamma and interleukin-17 in the spinal cord