Gene interactions and pathways from curated databases and text-mining

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EDN1 — EPO

Text-mined interactions from Literome

Banerjee et al., Kidney Int 2000 : We hypothesize that EPO receptors (EPORs) on endothelial cells ( ECs ) in various sites of vasculature may mediate the activities of nitric oxide synthase (NOS) and/or the release of endothelin-1 (ET-1) , contributing to blood pressure changes
Jelkmann et al., Ann Hematol 2004 (Neoplasms) : Epo promotes angiogenesis and stimulates the production of endothelin and other vasoactive mediators
Grenz et al., Naunyn Schmiedebergs Arch Pharmacol 2006 (Anoxia) : Effect of endothelin-1 on erythropoietin production in a rat model under normoxia and functional carbon monoxide induced hypoxia
Shah et al., Am J Perinatol 2010 (Retinopathy of Prematurity) : In addition to its hematopoietic effects, erythropoietin causes an increased release of endothelin-1 and the stimulation of angiogenesis and thereby it may have possible role in development of retinopathy of prematurity (ROP)
Simon et al., Rev Med Interne 1995 (Anemia...) : Recently, it was demonstrated that erythropoietin increased endothelin-1 release by endothelial cells
Kita et al., J Immunol 1995 : MBP ( 10 micrograms/ml ) and EPO ( 0.1 micrograms/ml ) induced EDN release comparable with one of the strongest agonists for eosinophils, secretory IgA ... Pretreatment of cells with dibutyryl cAMP or cytochalasin B completely abolished the EDN release induced by MBP and EPO , suggesting that the effects of MBP and EPO are not due to cytotoxic lysis of the cells
Hon et al., Artif Organs 1995 (Kidney Failure, Chronic) : Lack of a fast acting effect of erythropoietin on arterial blood pressure and endothelin level ... This study was designed to explore the presence, if any, of fast acting effects of EPO on the arterial blood pressure and endothelin level in vivo
Katoh et al., Life Sci 1994 : Direct evidence for erythropoietin induced release of endothelin from peripheral vascular tissue ... The effect of recombinant human erythropoietin ( r-HuEPO, 0.1 to 2.0 U/ml ) on endothelin-1 (ET-1) release was examined in isolated hind legs perfused with Krebs-Ringer solution from normal rats
Carlini et al., Kidney Int 1993 : Recombinant human erythropoietin ( rHuEPO ) increases endothelin-1 release by endothelial cells
López Ongil et al., Exp Nephrol 1996 : Recombinant human erythropoietin does not regulate the expression of endothelin-1 and constitutive nitric oxide synthase in vascular endothelial cells
Haller et al., Kidney Int 1996 : Erythropoietin (EPO) induces endothelin expression in endothelial cells ( EC ) and has angiogenic effects
Vogel et al., Am J Hypertens 1997 (Second Messenger Systems) : Effects of erythropoietin on endothelin-1 synthesis and the cellular calcium messenger system in vascular endothelial cells
Liefeldt et al., J Cardiovasc Pharmacol 1998 : Transcriptional regulation of endothelin-1 by erythropoietin in endothelial cells
Kang et al., Nephrol Dial Transplant 1998 : Acute effects of recombinant human erythropoietin on plasma levels of proendothelin-1 and endothelin-1 in haemodialysis patients