Gene interactions and pathways from curated databases and text-mining

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EIF4G1 — EIF4H

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Pilipenko et al., Genes Dev 2000 : Reconstitution of initiation using fully fractionated translation components indicated that 48S complex formation on both IRESs requires eIF2, eIF3, eIF4A, eIF4B, eIF4F , and the pyrimidine tract binding protein (PTB) but that the FMDV IRES additionally requires ITAF ( 45 ), also known as murine proliferation associated protein ( Mpp1 ), a proliferation dependent protein that is not expressed in murine brain cells
Jeske et al., EMBO J 2011 : The initiation factor eIF4G is specifically displaced, and 48S pre-initiation complex formation is inhibited