Gene interactions and pathways from curated databases and text-mining

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EPHA2 — VEGFA

Pathways - manually collected, often from reviews:

  • WikiPathways Focal Adhesion-PI3K-Akt-mTOR-signaling pathway: EFNA1/FGF1/FGF11/FGF10/EFNA2/EGF/FGF12/CSF1/ANGPT4/ANGPT2/ANGPT1/VEGFA/EFNA3/EFNA4/EFNA5/FGF14/FGF19/FGF17/FGF18/FGF2/FGF3/FGF4/FGF6/FGF7/FGF8/FGF9/FIGF/HGF/IGF1/INS/INS/KITLG/VEGFC/VEGFB/PDGFB/PGF/PDGFA/NGF/PDGFC/FGF21/FGF22/PDGFD/FGF20/FGF16 → FGFR2/KDR/INSR/FGFR3/IGF1R/KIT/FGFR1/EPHA2/EGFR/CSF1R/FGFR4/FLT1/FLT4/NGFR/MET/PDGFRA/PDGFRB/TEK (activation)

Text-mined interactions from Literome

Cheng et al., Mol Cancer Res 2002 (Corneal Neovascularization) : A soluble EphA2-Fc receptor inhibits VEGF- , but not basic fibroblast growth factor induced endothelial cell survival, migration, sprouting, and corneal angiogenesis
Liu et al., Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2013 (Carcinoma, Squamous Cell...) : [ EphA2 mediated vascular endothelial growth factor expression via the p38 MAPK signaling pathway in squamous cell carcinoma of the head and neck ] ... EphA2 can regulate the expression of VEGF protein and stimulate p38 MAPK signaling pathway