Gene interactions and pathways from curated databases and text-mining

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ERP44 — PCNA

Text-mined interactions from Literome

Nishiyama et al., Nature 2007 : Our results also suggest that Erp1 inhibits cyclin B degradation by binding the APC/C at its carboxy-terminal destruction box, and this binding is also enhanced by the Mos dependent phosphorylation
Kaur et al., Mol Cell Biochem 1998 : By using the specific blockers of ras farnesylation as well as phospholipase D, it became apparent that phosphatidic acid regulates two processes : ( a ) activation of Gap-ras pathway leading to the expression of c-fos, c-myc proto-oncogenes probably through the activation of NF1 transcription factor ; ( b ) cleavage of 125 kDa endoplasmic reticulum protein leading to the generation of 47 kDa protein factor which not only regulates mevalonate pathway but also has an ability to heterodimerize with Receptor-Ck protein and this heterodimer may be responsible for the regulation of cyclin ` D ' expression probably by binding to the SRE like sequence present in the promoter region of this gene