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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Winbanks et al., J Cell Biol 2012 (Hypertrophy) : Furthermore, we identify Smad3 as the critical intracellular link that mediates the effects of follistatin on mTOR signaling ... Expression of constitutively active Smad3 not only markedly prevented skeletal muscle growth induced by follistatin but also potently suppressed follistatin induced Akt/mTOR/S6K signaling ... Importantly, the regulation of Smad3- and mTOR dependent events by follistatin occurred independently of overexpression or knockout of myostatin, a key repressor of muscle development that can regulate Smad3 and mTOR signaling and that is itself inhibited by follistatin
Sun et al., J Cell Biol 2010 : Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis