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CD79B — HCK

Text-mined interactions from Literome

Lionberger et al., J Biol Chem 2000 (Leukemia, Myeloid) : Recent work shows that Hck , a member of the Src tyrosine kinase family with myeloid restricted expression, associates with and is activated by Bcr-Abl
Poincloux et al., J Cell Physiol 2007 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : In chronic myeloid leukemia ( CML ), the transforming activity of Bcr/Abl involves constitutive activation of the phagocyte specific Src-family tyrosine kinase Hck , which in turn directly activates the signal transducer and activator of transcription 5 ( STAT5 )
Pene-Dumitrescu et al., J Biol Chem 2010 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : NaPP1 also reduced Hck mediated phosphorylation of Bcr-Abl at sites that may affect imatinib sensitivity exclusively in cells expressing Hck-T338A
Warmuth et al., J Biol Chem 1997 : Neither the complex formation of Hck kinase with Bcr-Abl nor the activation of Hck by Bcr-Abl was dependent on the Abl kinase activity