Gene interactions and pathways from curated databases and text-mining

◀ Back to IGF1

IGF1 — INSRR

Pathways - manually collected, often from reviews:

  • KEGG Prostate cancer: EGF/IGF1/INS/PDGFA/PDGFB/PDGFC/PDGFD/TGFA → EGFR/ERBB2/FGFR1/FGFR2/IGF1R/INSRR/PDGFRA/PDGFRB (protein-protein, activation)

Text-mined interactions from Literome

Kovacina et al., J Biol Chem 1995 (Neuroblastoma) : The intrinsic tyrosine kinase activity of this endogenous IRR was activated by the agonist monoclonal antibody to IRR but not by nerve growth factor, insulin-like growth factor I , or insulin
Jui et al., J Biol Chem 1994 : However, proinsulin, insulin, IGF-I , and IGF-II did not stimulate tyrosine phosphorylation of the IRR ... However, proinsulin, insulin, IGF-I , and IGF-II did not stimulate tyrosine phosphorylation of the IRR